Claim adjustment reason code
CO-227: Requested information from the patient not supplied
CO-227 means: Information requested from the patient/insured/responsible party was not provided or was insufficient/incomplete. At least one Remark Code must be provided (may be comprised of either the NCPDP Reject Reason Code, or Remittance Advice Remark Code that is not an ALERT.) The payer asked the patient for something — very often about other insurance or an accident — and did not get it.
Read the group code before you act on this
227 is the reason. The CO in front of it is the group code, a separate field on the remittance, and it is the one that decides who owes the money: CO means contractual obligation — the payer says the amount is not billable to anybody, and it is written off unless the denial itself is overturned. You may not bill the patient. What the other group codes mean.
What causes CO-227?
- Coordination of benefits questionnaire sent to the patient and not returned
- Accident or injury details requested and not supplied
- Student or dependent status verification outstanding
- Payer wrote to an old address
How do you fix a CO-227 denial?
- Ring the payer and find out exactly what was asked of the patient and how they can supply it.
- Contact the patient and tell them specifically what to do — most of these sit unanswered because the payer’s letter was not understood.
- Many payers will accept the information over the phone from the patient, which is far faster than post.
- Resubmit or ask for reprocessing once the payer confirms it has what it needs.
Can CO-227 be prevented?
Ask about other coverage and about accident-related care at registration. A coordination of benefits question answered on day one never becomes this denial.
A denial like this one is the recurring cost that medical billing outsourcing is built to take off your desk — a dedicated seat working the queue instead of it waiting for whoever has a free hour.
Who does this work
A patient billing & statements seat at $1,600 per seat per month works this queue full time, during your business hours, inside your own system. Every call is logged with the payer reference number and the outcome, and every Friday you get it in writing.
Codes worked the same way
CO-227 is answered with the document the payer names. So are these, which is why a queue sorted by recovery route moves faster than one sorted by code number — the same person, in the same system, with the same evidence to hand, clears all of them in one pass.
- CO-252 — Additional documentation required
- CO-226 — Requested information not supplied
- CO-251 — Documentation incomplete
- N29 — Documentation missing
Specialties that name this among their costliest
These are specialties whose own worst denials include one of this kind. The line under each is the denial they name, quoted from their page so you can see what the link is based on.
- AnesthesiaTime units miscalculated from an incomplete anesthesia record
- OphthalmologyIntravitreal injection paid for the administration but not the drug, because the units given and the amount discarded were never written into the note.
- OtolaryngologyEndoscopic sinus surgery denied because the chart never pulls the failed medical management together — the drug trials, their dates and imaging findings sit in separate notes or nowhere.
- NeurologyNerve conduction study with needle EMG denied because the report gives only a summary impression instead of each nerve and muscle tested with its findings
- Obstetrics & GynecologyGlobal maternity package billed in full after the patient transferred care mid-pregnancy, when only the antepartum visits actually rendered here should have been itemised.
- Urgent CareLaceration repair paid at the simplest level because the note says the wound was closed but never records its length, its site or whether the closure was layered
What leaving it costs
Working a denied claim costs $57.23 per denied claim in administrative time (source) — before any of it is recovered, and whether or not it ever is.
Payers ultimately pay roughly 90% of claims even while using an initial denial to slow payment (source), so the reason one sits is rarely that nobody knows how to work it. Put your own denial count in.
Questions
What does denial code CO-227 mean?
Information requested from the patient/insured/responsible party was not provided or was insufficient/incomplete. At least one Remark Code must be provided (may be comprised of either the NCPDP Reject Reason Code, or Remittance Advice Remark Code that is not an ALERT.) In plain terms: The payer asked the patient for something — very often about other insurance or an accident — and did not get it.
What causes CO-227?
Coordination of benefits questionnaire sent to the patient and not returned. Accident or injury details requested and not supplied. Student or dependent status verification outstanding. Payer wrote to an old address.
How do you fix a CO-227 denial?
Ring the payer and find out exactly what was asked of the patient and how they can supply it.. Contact the patient and tell them specifically what to do — most of these sit unanswered because the payer’s letter was not understood.. Many payers will accept the information over the phone from the patient, which is far faster than post.. Resubmit or ask for reprocessing once the payer confirms it has what it needs..
Can CO-227 be prevented?
Ask about other coverage and about accident-related care at registration. A coordination of benefits question answered on day one never becomes this denial.
Is CO-227 the same as PR-227?
Same reason, different group code. The number 227 is the reason: The payer asked the patient for something — very often about other insurance or an accident — and did not get it. The prefix says who carries the amount. CO means contractual obligation — the payer says the amount is not billable to anybody, and it is written off unless the denial itself is overturned. PR-227 is the same reason assigned to patient responsibility — the payer says the amount is owed by the patient, and it is billed to them. Read the prefix before the number: it decides whether you appeal, write off, or bill the patient.
What is the difference between CO-227 and CO-226?
CO-227: The payer asked the patient for something — very often about other insurance or an accident — and did not get it. CO-226: The payer asked you for something, and either nothing arrived or what arrived did not answer the question. They are different reasons that happen to sit next to each other in the list, and they are worked differently — CO-227 is answered with the document the payer names; CO-226 is answered with the document the payer names.
Code descriptions are the standard X12 claim adjustment reason and remittance advice remark code text. Payer policies differ, and the payer’s own coverage policy governs any individual claim. This page is working guidance, not legal or clinical advice.
Last updated 2026-09-14. This is operational guidance drawn from payer remittance practice, not legal, coding or reimbursement advice. Payer-specific rules vary and change; confirm against the payer’s own policy before acting on a specific claim.
Other denial codes
- CO-226 — Requested information from the provider not supplied
- CO-22 — May be covered by another payer
- N29 — Missing documentation, orders, notes or report
- CO-251 — Attachment or documentation incomplete or deficient
- CO-16 — Claim lacks information or has a submission error
- N382 — Missing, incomplete or invalid patient identifier
- How long payer enrollment actually takes
- Why prior authorizations get delayed, and how to stop it
- How to find payer underpayments nobody is looking for
Next step
Is CO-227 one of the denials costing you most?
Send a ninety-day denial report and an aged AR summary, with no patient identifiers. Within two working days you get a written summary of which denial reasons are costing you most and what is recoverable.
Or write to ops@softhomeglobal.com

